So, how can we detect it early?
From our center we encourage all owners of dogs and cats over 7 years to take a urine sample. So we can do a urine labwork, to evaluate the health of pet kidney, showing urinary sediment, the urine gravity and the amount of protein in urine.
The first step is to perform with a portion of the sample a centrifugation to obtain all that solid material (urinary sediment), which is then evaluated after staining it under microscope, looking for crystals and cells infection or inflammation cells. If it comes out positive, we must treat the disease properly assessed and then evaluate again protein and garvity to avoid false positives. Once solved the problem, we can routinely evaluate specific parameters.
If this sediment out negative, we proceed to determine the urine gravity. In general, if a cat has values below 1035 and a dog under 1012, is considered to be the early stages of chronic renal failure. In dogs, we also do a urine strip, determining qualitatively the presence of protein, glucose, white blood cells, among other things in the urine. Depending on the amount of protein that the strip shows (which may be from negative to 4+) the measurement of protein will be taken. In cats, the protein is measured directly, since the strip is considered unlikely.
Finally, we measure the amount of proteinuria presented by the animal by a protein/creatinine ratio (UPC ratio), which is a reflection of the amount of protein excreted in urine within 24 hours.
Once we have the results, we can say that: the animal does not have proteinuria, that is border line- 1 month revaluation is recommended- or that is presenting proteinuria- start to treat it. In addition, depending on the results of the tests, blood tests may be required to evaluate renal blood indicators or measuring systolic blood pressure.
With all the results we will tell you what is the most appropriate treatment, as well as veterinary follow-up schedule most appropriate.